What is PCC1 (ProcyanidinC1)?
Powerful Natural Composition
PCC1 is derived from grape seeds and pine bark, making it one of the most potent procyanidins. It has been safely consumed for generations, standing the test of time.
Targeted Clearance of Senescent Cells
PCC1 selectively eliminates senescent cells, promoting healthy aging and cellular rejuvenation.
Proven Safety
Long-term dietary use has confirmed PCC1ʼs safety, highlighting its potential therapeutic value in longevity and health optimisation.
What is Senescent Cell
Senescent cells originate from normal cells but enter a metabolic arrest phase (G1 phase) where they neither proliferate nor die. They can even attack surrounding healthy cells, causing them to become senescent as well. Due to this characteristic, they are often referred to as “Zombie Cells.”
What are the Factors That Trigger or Promote Cellular Senescence?
Cellular senescence can be triggered by various stressors, including DNA damage, metabolic stress, chronic inflammation, and tissue injury.
· DNA damage, such as that caused by radiation or replication errors, activates cellular checkpoint pathways that halt cell division.
· Metabolic stress, often resulting from mitochondrial dysfunction or nutrient imbalance, disrupts normal cellular functions and promotes senescence.
· Chronic inflammation, driven by persistent harmful stimuli, creates a pro-senescent environment through inflammatory cytokines and oxidative stress.
· Lastly, tissue damage—whether mechanical or chemical—can induce senescence as a protective mechanism to prevent the proliferation of potentially compromised cells.
Do Senescent Cells Affect Healthy Cells?
Senescent cells continuously secrete senescence—associated secretory phenotype (SASP) factors and inflammatory signals such as reactive oxygen species (ROS), which induce senescence in surrounding cells. This process amplifies the spread of senescent cells, leading to a bystander effect.
Do Senescent Cells Naturally Undergo Apoptosis?
Protected by senescence—associated anti—apoptotic pathways (SCAPs),senescent cells evade natural cell death. Due to their SASP secretions, they persist in biological environments, avoiding clearance by the immune system.
When senescent cells (black line) exceed the critical threshold, disease onset occurs. Each individual accumulates senescent cells differently, which explains the variation in the timing of disease development.
Multiple age-related diseases follow a similar pattern
Disease incidence rates increase by 6–8% per year before stabilising later in life. Data from 500,000 patients confirm this trend.
When you start to feel a decline in your bodily functions, these things are happening
The right figure shows the 12 hallmarks of ageing proposed :
199 PCC1 Clinical Results
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Cell Health
27% reduction in senescence-associated secretory phenotype (SASP) signals, promoting cellular rejuvenation.
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Inflammation Balance
Key inflammatory factor lL-6 decreased by 17%, helping alleviate chronic inflammation.
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Heart and Brain Health
VEGF decreases by 23.7%, promoting heart and brain health, and improving focus.
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Enhanced Recovery
TGF-β1 decreases by 66.8%, reducing tissue fibrosis and enhancing repair ability.
How should this product be stored?
Store in a cool, dry place, away from direct sunlight.
Is PCC1 safe during pregnancy or breastfeeding?
Before taking PCC1 or any supplement during pregnancy or breastfeeding, consult a medical professional or healthcare provider.
Can I take this product with other medications or supplements?
While PCC1 is generally safe, if you are currently taking medication, please consult a healthcare professional before combining it with other treatments.
How long does it take to see results?
Many users notice changes within 7-14 days, often experiencing increased energy levels and mental clarity.
What does “clinically proven” mean?
Our formulation has undergone multiple volunteer trials before release, ensuring reliable and consistent results